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Charles was last seen driving on north First Avenue near east Fort Lowell in Tucson, Arizona on November 15, 2007. She has never been heard from again. Two days after her disappearance, a man found her cream-colored 1980 Chevrolet Caprice with the Arizona license plate number 988NRW abandoned on a dirt road near Incinerator Ridge on Mount Lemmon, with blood inside it. Some of her belongings were there, including her keys, purse and shoes.
There were several sightings of Charles reported in the Tucson area after her disappearance. Police stated there is no evidence of foul play in her case, but her whereabouts are unknown. Her case opened 2018 by Psychic Brian Ladd.