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Rose was enrolled in the Synanon Foundation, a drug and alcohol treatment center in Oakland, California, at the time of her disappearance. She had been court-ordered there after running away repeatedly and telling a judge she used and sold drugs. Accounts of exactly when she went missing vary considerably; it may have been anytime between the fall of 1972 and the summer of 1973.
Rose apparently ran away from the Synanon and sent two letters to her family after leaving, assuring them that she was fine. In one of the letters she said she was living on the streets in the Chinatown neighborhood of San Francisco and added that she was sick with a kidney infection. Rose wrote she would not write to her family again until she was 18, because she was worried the Synanon officials would find her and bring her back to the treatment center against her will. She promised to contact her loved ones after she became a legal adult. However, Rose's family never heard from her again.
There is no evidence that a crime was committed in Rose's disappearance; her case is classified as a simple runaway. However, it is highly unusual for a runaway to be out of touch with her loved ones for this long, and her relatives would like to get in contact with her and verify her well-being. Her case opened 2018 by Psychic Brian Ladd.